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Biostimulators

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What Are Biostimulators?

Biostimulators are injectables that stimulate the body’s natural collagen production, offering gradual and natural-looking enhancements over time.  Unlike traditional fillers, which add volume by filling in wrinkles, biostimulators activate collagen synthesis, improving skin elasticity and structure. This biostimulation process triggers the immune system by activating fibroblasts, effectively preventing collagen loss and reducing the signs of facial aging. The effects of biostimulators develop over weeks to months, resulting in subtle outcomes compared to traditional fillers that provide instant volume.

What Are the Indications for Biostimulator Injections?

Biostimulator injections are versatile treatments suitable for various areas of the body, aimed at enhancing skin quality and promoting collagen production. They’re ideal for patients looking to mitigate signs of aging and enhance skin vitality without the immediate volume effects associated with traditional dermal fillers. Biostimulators are commonly used for:
  • Face: Reducing fine lines, wrinkles, and improving overall skin texture and tone
  • Neck: Addressing signs of aging and enhancing skin firmness and elasticity
  • Décolleté: Minimising crepiness and improving skin hydration and appearance
  • Body: Treating areas with skin laxity or uneven texture
  • Hands: Restoring volume and improving skin quality, making the hands appear more youthful

Top Biostimulator Brands

There are two main categories biostimulators fall into - hyaluronic acid based and non-HA based. This includes PLLA, PDLLA, PCL, and polynucleotides, which focus on collagen stimulation but provide less hydration than HA-based injectables. We offer a wide range of top biostimulator products from both these categories, including:
  • Belotero Balance and Belotero Balance with Lidocaine, known for their ability to integrate smoothly into the skin, providing subtle and even results
  • Ellanse S and Ellanse M - innovative biostimulators that not only stimulate collagen production but add volume at the same time
  • Juvederm, renowned for its versatile range of products  offers options that enhance hydration and collagen stimulation such as Juvederm Voluma and Juvederm Volbella
  • Perfectha Subskin which is designed to restore volume and improve skin quality
  • Radiesse, an injectable treatment that provides results lasting up to 15 months
  • Restylane Lyft,  one of the best choices for eye region improvement
  • Teosyal RHA range enhance skin elasticity and hydration, with options tailored for various aesthetic needs

Results and Benefits of Biostimulators

  • Gradual enhancement as the collagen production is stimulated over time, leading to subtle improvements in skin elasticity and firmness rather than immediate volume changes
  • Counteract the natural decline of collagen associated with aging, reducing the
  • Patients often notice better skin texture, reduced fine lines, and minimised pore size, contributing to an overall rejuvenated appearance
  • Depending on the specific biostimulator used, results can last from several months to a few years, making them a cost-effective option for long-term skin health
  • Fully customised treatment, allowing for personalised care
  • Many patients experience skin tightening and lifting in key areas, enhancing facial contours and overall facial harmony
  • Most biostimulators require little to no recovery time, making them convenient for individuals seeking effective treatments without extended disruptions to their daily routine

How Long Do Biostimulators Last?

The results of biostimulators can last from several months to a few years, influenced by the specific product used and individual factors like age and lifestyle. Initial effects may be visible after a few weeks, with full results developing gradually. Follow-up treatments are often recommended to maintain optimal results.

Biostimulators Pre-Treatment and Aftercare

To achieve optimal results and minimise potential side effects from biostimulator injections, it is essential to follow proper pre-treatment and aftercare guidelines. During the pre-treatment consultation, review the patient's medical history and discuss treatment goals. Patients should avoid blood-thinning medications, such as aspirin or ibuprofen, for at least one week before the treatment to reduce the risk of bruising. Staying well-hydrated in the days leading up to the treatment can help maintain skin hydration. Additionally, it is advisable to refrain from harsh treatments, such as chemical peels or strong exfoliants, for at least one week prior to the injection.   Recovery times can vary depending on the injectable used, typically ranging from immediate recovery to a 48-hour period. Aftercare instructions include applying a cold compress to the injection sites if swelling or discomfort occurs and avoiding touching or massaging the treated areas for at least 24 hours to prevent product displacement. Patients should also refrain from applying makeup during this time. Protecting the skin from excessive sun exposure and using sunscreen can minimise potential irritation. Finally, it is recommended to avoid strenuous exercise and activities that may increase blood flow to the face for 24 to 48 hours post-treatment. Following these guidelines can enhance the effectiveness of biostimulator injections and improve overall results.

Potential Side Effects

Common mild and temporary side effects of biostimulators include swelling, redness, minor bruising, and tenderness at injection sites. Some may occasionally lead to small nodules or lumps, which typically soften over time. Patients should follow post-treatment care instructions to minimise these effects and report any persistent or concerning symptoms to their healthcare provider.

Biostimulators Contraindications

Patients should consult with their healthcare provider to determine if this treatment is appropriate for them as biostimulator injections may not be suitable for everyone. It's crucial to understand the contraindications to ensure safety and effectiveness. Contraindications include:
  • Women who are pregnant or breastfeeding
  • Individuals with known allergies to any components in biostimulators
  • Patients with active infections or inflammation in the treatment area
  • Patients with autoimmune diseases 
  • Individuals with severe medical conditions, including heart disease or bleeding disorders
  • Those who have undergone recent surgery in the treatment area should wait until fully healed before considering biostimulator injections
  • Tendency to form keloids

Who Can Buy Biostimulators and Where?

Biostimulators are professional-grade injectable treatments, primarily intended for use by licensed medical professionals such as dermatologists, cosmetic surgeons, and trained practitioners in aesthetic medicine. These injectables require proper expertise for safe and effective application. For safety and quality assurance, it is important to buy biostimulators from reputable and authorised suppliers, such as Best Buy Fillers. This ensures that the products are genuine, safe, and compliant with regulations. Explore our range of biostimulators and buy biostimulators online today.

FAQ

Do biostimulators really work?

Yes, biostimulators are effective in stimulating collagen production, leading to gradual improvements in skin firmness, elasticity, and texture. Unlike traditional fillers that provide instant volume, biostimulators work over time, offering a more natural-looking rejuvenation.

How many treatments will I require?

Patients often see noticeable results, including reduced fine lines and smoother skin, after multiple sessions. The results vary based on factors like age, skin condition, and the specific product used, but biostimulators are a proven method for long-lasting anti-aging benefits.

Are biostimulator injections safe?

Yes, biostimulator injections are generally safe when administered by qualified professionals. The materials used, such as poly-L-lactic acid (PLLA) and calcium hydroxylapatite (CaHA), are biocompatible and have been safely used in medical applications for years. So although, as with any cosmetic procedure, there can be potential risks and side effects, overall, they are considered safe for most individuals.

Are biostimulators painful?

Biostimulator injections are generally well-tolerated, with most patients experiencing only mild discomfort. The level of pain varies depending on the product used and the individual’s sensitivity. Many formulations contain anaesthetics like lidocaine to minimise discomfort during the procedure.

Is Profhilo a biostimulator?

Yes, Profhilo is considered a biostimulator. It is an injectable skin remodeling treatment with one of the highest concentrations of hyaluronic acid available. Profhilo is specially designed for individuals with skin that lacks volume and elasticity, promoting collagen and elastin production to improve skin texture, hydration, and firmness over time.

What is the difference between biostimulators and fillers?

Biostimulators trigger collagen production, offering gradual improvements in skin elasticity and structure. They primarily target the skin’s upper layers and focus on long-term rejuvenation with minimal changes to volume. Dermal fillers, on the other hand, provide immediate volume by filling in wrinkles or hollow areas. They are used to correct volume loss from fat and bone atrophy, providing more immediate results than biostimulators.

What is the difference between biostimulators and skin boosters?

Biostimulators and skin boosters both aim to improve skin quality, but they work in different ways. Biostimulators primarily stimulate collagen production, providing gradual improvement in skin elasticity and structure. They focus on long-term skin rejuvenation by encouraging the body’s natural repair mechanisms. Skin boosters, on the other hand, mainly hydrate the skin. They use hyaluronic acid to improve moisture levels, resulting in smoother, plumper skin. Unlike biostimulators, skin boosters do not trigger collagen production but focus on immediate hydration and skin texture improvement.

Is hyaluronic acid a biostimulator?

Yes, hyaluronic acid can act as a biostimulator in certain formulations. While traditional HA fillers primarily add volume and hydration to the skin, newer injectable treatments like Profhilo use hyaluronic acid to stimulate collagen and elastin production. These HA-based biostimulators focus on improving skin quality, elasticity, and hydration over time.

Are biostimulators permanent?

No, biostimulators are not permanent. The effects of biostimulator injections gradually develop as they stimulate the body’s natural collagen production, typically lasting several months to over a year, depending on the specific product used and individual factors. Over time, the body metabolises the substances, and the effects will diminish, requiring follow-up treatments to maintain the desired results.

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