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Croma Pharma

What Is Croma Pharma?

Croma-Pharma GmbH, commonly known as Croma, is a family-owned company that has grown into a global player in the rapidly evolving world of minimally invasive aesthetics. Founded in 1976 by pharmacists Gerhard and Karin Prinz in Vienna, Austria, Croma began as a small operation focused on producing high-quality medical products. Today, the company is recognised as a leader in the industry, particularly in the manufacturing of premium hyaluronic acid (HA) syringes.

Croma focuses on minimally invasive aesthetic medicine with its own branded products. In addition to a wide range of HA fillers produced in-house, Croma also offers PDO lifting threads, a Platelet Rich Plasma (PRP) system, botulinum toxin, skin boosters and personalised skincare technology.

Croma Pharma Manufacturing 

To meet the growing demand for its products, Croma invested in a state-of-the-art manufacturing facility, which opened in 2018. This fully automated site is dedicated to producing hyaluronic acid fillers using an innovative crosslinking technology developed in-house. This technology aligns HA chains and cross-links them using BDDE, creating a stable three-dimensional matrix. The result is a high-quality HA gel with enhanced viscosity, cohesiveness, and stability.

Croma’s commitment to quality is evident in every aspect of its production process. The company’s manufacturing lines are highly automated, minimising human influence and ensuring consistent product quality. During the filling process, Croma employs a restricted area barrier system (RABS) and terminal sterilisation to reduce the risk of contamination, ensuring the highest standards of safety and hygiene.

What Are Croma Products Used for?

Croma’s products are versatile, addressing a wide range of aesthetic concerns. Depending on the product, they can be used to treat:

  • Loss of skin firmness
  • Wrinkles and fine lines
  • Volume loss
  • Skin rejuvenation
  • Scarring and imperfections
  • Loss of skin tone and elasticity
  • Alopecia 

Croma Pharma Products Range

Croma offers a very wide range of products that can be categorised under the following categories:

HA Fillers, such as their well-known Saypha range of products:

  • Saypha Rich replenishes hyaluronic acid, improving skin hydration, tone, elasticity, and correcting fine lines by injection into the superficial dermal layer.
  • Saypha Filler and Saypha Filler Lidocaine correct moderate to severe facial wrinkles, with the latter also increasing lip volume, injected into the mid to deep dermis.
  • Saypha Volume and Saypha Volume Lidocaine correct deeper wrinkles, build facial volume, and remodel facial contours by injecting into the deep dermis or subcutis.
  • Saypha Volume Plus Lidocaine augments facial tissue to correct midface volume deficits, contour the face, and treat conditions like facial lipoatrophy, injected subcutaneously, supraperiosteally, or into the deep dermis.

Skin boosters, which is their PhilArt range (previously known as Juvenus): 

  • PhilArt boosts skin radiance and rejuvenation, perfect for both young and mature skin, and can be used on the face, neck, décolletage, and hands.
  • PhilArt Eye revitalises the delicate skin around the eyes, suitable for patients of all ages.
  • PhilArt Next delivers advanced skin rejuvenation for all skin types and ages, effective on the face, neck, décolletage, and hands.
  • PhilArt Hair supports scalp health and hair rejuvenation, ideal for all skin types and ages, specifically targeting the scalp.

Croma skincare, which entails several brands like:

  • Masks
  • Elure, which is a brand of products like Advanced Brightening Lotion, Advanced Facial Wash and Brightening Night Cream
  • Pure HA, which is a line of highly concentrated liquid skin mask of pharmaceutical grade ingredients.

PDO Threads, which are their Princess Treads used as a non-surgical alternative to facelifts. There are varying sizes and properties, subcategorised under Screw, Basic and Barb.

The brand also carries some other products necessary for beauty treatments, like needles and local anaesthesia, as well as few products for personalised cell therapy (PRP and Lipofilling). 

Benefits of Using Croma Products

  • Natural results: Effective and natural outcomes with a solid scientific foundation, ensuring high quality and optimal results through a tailored treatment plan
  • Pain-free & safe: Minimal bruising and discomfort with resorbable products that offer excellent tissue tolerability and reduced risk
  • No surgery, no downtime: Achieve results previously only possible with surgery, without the need for hospitalisation or recovery time
  • Visible results: Treatments provide clear, noticeable improvements with scientifically backed methods and a professional approach
  • State-of-the-art manufacturing: Advanced, fully automated production site established in 2018 for high-quality aesthetic products
  • High stability & safety: Automated production lines ensure consistent quality and minimise contamination risks through advanced aseptic techniques

Longevity of the Results

Typically, the results can last for several months up to a year, depending on the product used, the injection area and the skin’s unique characteristics

To maintain the results, regular follow-up treatments are recommended. The frequency will be determined individually by the treatment provider since there are several factors that can affect how long the results last, including the client’s lifestyle, level of physical activity, sun exposure, and age.

Recommendations Before and After the Treatment

Before treatment, discuss the goals and expectations with your clients. Go through previous medical history, including any prior aesthetic treatments. If the client is on anticoagulant medication, it’s recommended to pause it for 14 days before the procedure.

To achieve the best results, clients need to adhere to a few guidelines. Most importantly, avoiding touching the treated areas on the day following the treatment. Also, they should refrain from applying makeup to the treated areas for at least 12 hours and avoid sun exposure, high temperatures, saunas, and steam rooms for the first week.

Potential Side Effects

Although Croma adheres to the highest quality standards to ensure product safety and effectiveness, some post-treatment discomfort or side effects may still occur – either immediately after the injection or at a later time.

It’s important for patients to promptly inform their aesthetic practitioner if they experience any inflammatory reactions or other adverse events, so they can provide appropriate care.

Contraindications for the Treatment

Treatments with most Croma products are not suitable to be used by individuals with:

  • History of autoimmune disease or currently on immunosuppressants
  • Hypersensitivity to hyaluronic acid, lidocaine, or amide-type local anaesthetics
  • Pregnant or breastfeeding women
  • People under 18 years old
  • An ongoing herpes infection
  • Tendency to develop hypertrophic scarring or have a susceptibility to keloid formation

Who Can Buy Croma Pharma Products?

Chroma products are meant to be purchased only by authorised medical professionals. When buying online, always choose certified and authorised vendors like Best Buy Fillers to ensure the product’s authenticity and safety. This helps avoid counterfeit items and ensures both patient safety and successful treatments.


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