What is Restylane? All You Need to Know About Restylane Dermal Filler

Restylane is an established dermal filler brand known for its consistent results, advanced hyaluronic acid formulations, and a wide product range. The product line was approved by the FDA in 2003. Thanks to the longevity, safety, and effectiveness of this dermal filler, it makes it a common choice among medical aestheticians. For medical professionals, Restynale offers and rich portfolio that meets different patient needs, from subtle lip restoration to structural midface volume restoration. 

What is Restylane

Restylane is a family of injectable dermal fillers made of non-animal hyaluronic acid (NASHA). Hyaluronic acid naturally occurs in the body, and tos role is to retain moisture, plump tissues, and support elasticity. The NASHA technology in Restylane mimics natural HA but is engineered to resist enzymatic degradation, providing longer-lasting effects.

Developed by Q-Med and now manufactured and distributed by Galderma, Restylane represents over two decades of clinical use and innovation. Its safety and efficacy are supported by extensive clinical studies and global usage across a range of cosmetic and reconstructive indications.

How It Works

Restylane works by injecting HA-based gel into targeted areas of the skin. Once injected, the gel binds with water molecules, adding volume, smoothing lines and wrinkles, and enhancing facial contours. The result is immediate and natural-looking, with effects that evolve subtly as the filler integrates with tissue.

There are two core HA technologies used in the Restylane portfolio:

• NASHA (Non-Animal Stabilised Hyaluronic Acid): Offers firmer gels ideal for more structural work like nasolabial folds or cheeks.
• XpresHAn Technology (also known as OBT – Optimal Balance Technology): Provides more flexible gels that adapt to facial movements, ideal for dynamic areas such as lips or nasolabial folds.

The dual technology platform allows practitioners to choose between firmer support or softer, more elastic results based on the treatment area and desired outcome.

Indications & Treatment Areas

Restylane products are used for both aesthetic and reconstructive purposes. Common treatment areas include:

• Lips: Volume, shape, and definition.
• Nasolabial folds: Softening moderate to severe lines.
• Tear troughs: Reducing hollowness and shadowing under the eyes.
• Cheeks and midface: Restoring volume and contour.
• Chin and jawline: Enhancing definition.
• Hands: Rejuvenating appearance and masking veins/tendons.

FDA-approved indications vary by product but commonly include lip augmentation, correction of moderate to severe facial wrinkles, and volume restoration in the hands. Off-label uses (at the discretion of trained professionals) may include temple augmentation or nose reshaping.

Restylane Product Range

The Restylane portfolio includes a broad spectrum of products designed to suit different indications, tissue depths, and treatment goals:

• Restylane-L: Classic HA filler with lidocaine for moderate facial wrinkles and lips.
• Restylane Lyft: Thicker gel for midface volume, cheeks, and hands.
• Restylane Silk: Fine particle gel for subtle lip enhancement and perioral lines.
• Restylane Kysse: Designed for flexible, natural-looking lip augmentation using XpresHAn technology.
• Restylane Refyne & Restylane Defyne: Mid-range gels that maintain expression in dynamic areas; great for nasolabial folds and marionette lines.
• Restylane Contour: Created specifically for cheek definition with flexible integration.
• Restylane Eyelight: Tailored to under-eye hollows with minimal swelling and high safety profile.
• Restylane Skinboosters: Microinjections of HA for skin hydration and texture improvement, not for volumising.

All formulations are available with or without lidocaine. The range varies in terms of elasticity, viscosity, and particle size, giving practitioners the precision to customise every treatment/

Benefits for Practitioners

Medical aestheticians appreciate Restylane for its predictability, safety, and patient satisfaction. So let’s go over some of the key advantages of the filler: 

• High biocompatibility and minimal risk of allergic reactions.
• Immediate results with natural integration over time.
• Reversible with hyaluronidase if needed.
• Versatile portfolio suitable for nearly all facial zones.
• Dual HA technologies (NASHA and XpresHAn) for tailored results.
• So, how long does Restylane last? Well, the longevity ranges from 6 to 18 months, depending on the product.

With decades of clinical data and strong brand recognition, Restylane allows practitioners to confidently treat a wide variety of facial types, ages, and aesthetic goals.

Administration and Safety

Restylane injections must be administered by licensed healthcare professionals trained in facial anatomy and injection techniques. Proper technique reduces the risk of complications and ensures optimal results.

However, it is normal for certain side effects to occur, so let’s take a look at those. Common side effects include:

• Redness
• Swelling
• Bruising
• Tenderness
• Mild discomfort at the injection site

These typically resolve within a few days. On the other hand, rare complications include vascular occlusion, lumps, or allergic reactions. That is why it is essential to have reversal agents (like hyaluronidase) and emergency protocols in place.

After the treatment, patients should avoid intense heat, alcohol, and strenuous exercise for 24–48 hours. They should be advised about the possibility of temporary swelling or bruising, especially in delicate areas like the lips or eyes.

Restylane vs Other Fillers

When compared to competitors such as Juvederm and Teosyal, Restylane stands out for several reasons:

• Particle size customisation: Restylane offers more granular control.
• Firmer gels: Better suited for sculpting and structural support.
• Flexibility (XpresHAn): Provides natural movement in dynamic areas.
• Reputation and safety profile: Over 50 million treatments worldwide.

While Juvederm may be preferred for ultra-smooth textures, and Teosyal for hydration-focused treatments, Restylane delivers balanced, long-lasting results that practitioners can rely on across a wide patient demographic.

Why Stock Restylane in Your Clinic

Restylane’s popularity and clinical reliability make it a valuable addition to any aesthetic practice. Benefits of offering Restylane include:

• Strong brand recognition that builds patient trust.
• Broad treatment applicability, from fine lines to volume restoration.
• Proven track record of safety and effectiveness.
• Support from Galderma, including marketing materials and training resources.

Stocking Restylane enhances your clinic’s service offerings, allowing for highly customised treatment plans and improved patient satisfaction.

Conclusion

Restylane is a scientifically advanced, clinically proven dermal filler system that offers medical aestheticians flexibility, precision, and consistent patient outcomes. Backed by Galderma’s ongoing innovation, Restylane provides a reliable toolkit for facial rejuvenation and enhancement. For aesthetic clinics seeking dependable results across a wide spectrum of treatments can buy Restylane at the Best Buy Fillers online store. Restylane 

References:

Tiwari S, Bahadur P. Modified hyaluronic acid based materials for biomedical applications. International Journal of Biological Macromolecules. 2019;121:556-571. https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/restylane

Martin TA, Harrison G, Mansel RE, Jiang WG. The role of the CD44/ezrin complex in cancer metastasis. Critical Reviews in Oncology/Hematology. 2003;46(2):165-186. https://www.sciencedirect.com/topics/medicine-and-dentistry/restylane

Rohrich RJ, Ghavami A, Crosby MA. The Role of Hyaluronic Acid Fillers (Restylane) in Facial Cosmetic Surgery: Review and Technical Considerations. Plastic and Reconstructive Surgery. 2007;120(Supplement):41S54S. https://pubmed.ncbi.nlm.nih.gov/18090342/