What Are Polynucleotides and How They Differ From Other Aesthetic Treatment Products

Understanding Polynucleotides in Aesthetic Medicine

Polynucleotides are rapidly emerging as a groundbreaking solution in regenerative aesthetics, offering unique skin-rejuvenating properties that set them apart from traditional treatments. But what are polynucleotides, and why are they gaining popularity among medical aestheticians?

Unlike hyaluronic acid fillers, platelet-rich plasma (PRP), or exosome therapies, they work at a cellular level to enhance skin regeneration, improve hydration, and promote tissue repair. These DNA-derived molecules stimulate fibroblast activity, increase collagen production, and support overall skin health, making them an excellent option for patients looking for long-term skin improvement.

In this guide, we’ll explore what are polynucleotides, their mechanism of action, key benefits, and how they compare to other aesthetic treatments. We’ll also discuss their most common applications, including under-eye rejuvenation, scar repair, and hair restoration.

How Do Polynucleotides Work?

Polynucleotides (PN) are biopolymers composed of long chains of nucleotides, the basic building blocks of DNA and RNA. These molecules play a crucial role in cell repair and regeneration by stimulating fibroblasts, which are responsible for collagen and elastin production.

What Are Polynucleotides Made Of?

Polynucleotides used in aesthetic medicine are typically derived from purified salmon or trout DNA, as these sources have a high biocompatibility with human tissue. The DNA is processed to remove immunogenic components, ensuring it is safe for injection into the skin.

Mechanism of Action

Once injected, polynucleotides work in several key ways:

• Fibroblast Stimulation: Encourages the production of collagen and elastin for firmer, more youthful skin.
• Deep Hydration: Polynucleotides attract water molecules, enhancing skin moisture levels.
• Antioxidant and Anti-Inflammatory Properties: They reduce oxidative stress and inflammation, making them ideal for sensitive or damaged skin.
• Tissue Repair and Regeneration: They help repair damaged skin by promoting cellular turnover and accelerating wound healing.

Key Benefits of Polynucleotides in Aesthetics

Polynucleotides offer a variety of benefits that make them a preferred choice for patients looking for a natural and regenerative approach to skin rejuvenation.

1. Long-Term Skin Regeneration

Unlike hyaluronic acid fillers that provide immediate volume, polynucleotide injections work progressively, improving the skin’s structure over time.

2. Improved Hydration and Elasticity

Polynucleotides enhance skin hydration at a deep level, improving elasticity and preventing premature aging.

3. Safe and Biocompatible

Since they are derived from natural sources and free from harmful chemicals, they are well-tolerated by most patients.

4. Reduced Inflammation and Oxidative Stress

Their ability to combat inflammation makes them beneficial for treating redness, rosacea, and sensitive skin conditions.

5. Natural and Subtle Results

Polynucleotides do not alter facial features like traditional fillers. Instead, they gradually improve skin texture and quality, making them ideal for patients seeking a refreshed, natural look.

Polynucleotides vs Other Aesthetic Treatments

How do polynucleotides compare to other popular aesthetic treatments? Let’s break it down.

Treatment	Main Function	Duration of Results	Best For
Polynucleotides	Stimulates collagen, repairs tissue, hydrates skin	6-12 months	Skin regeneration, hydration, fine lines
Hyaluronic Acid Fillers	Adds volume, fills wrinkles	6-24 months	Facial volume restoration, deep wrinkles
PRP (Platelet-Rich Plasma)	Uses growth factors to rejuvenate skin	6-12 months	Skin texture improvement, hair restoration
Skin Boosters	Hydration and mild collagen stimulation	3-9 months	Hydration, fine-line reduction
Exosome Therapy	Cellular regeneration and repair	Varies	Anti-aging, scar reduction, pigmentation

Key Differences

• Polynucleotides focus on tissue repair and long-term skin improvement, whereas HA fillers provide immediate volume.
• Compared to PRP products, polynucleotides offer more consistent and predictable results.
• Skin boosters hydrate, but polynucleotides also stimulate collagen and elastin production for enhanced skin quality.

Applications of Polynucleotide Treatments

Polynucleotide injections have a wide range of applications in aesthetic medicine, making them a versatile tool for medical aestheticians.

1. Skin Rejuvenation

They improve overall skin texture, elasticity, and hydration, helping to reduce fine lines and wrinkles.

2. Under-Eye Treatment

They are particularly effective for dark circles, fine lines, and crepey skin under the eyes, providing a refreshed, youthful look.

3. Scar and Wound Healing

They promote faster healing of acne scars, surgical scars, and stretch marks by stimulating tissue regeneration.

4. Hair Restoration

By improving scalp health and boosting follicle regeneration, polynucleotide injections can help combat hair thinning and stimulate hair growth.

Why Polynucleotides Are Gaining Popularity in Aesthetic Medicine

Polynucleotides are revolutionizing regenerative aesthetics due to their ability to restore skin quality from within. Unlike traditional fillers that provide temporary plumping, polynucleotides stimulate the body’s natural repair processes, leading to gradual and long-lasting skin rejuvenation.

Polynucleotide Treatments Available

For medical professionals looking to integrate polynucleotide treatments into their practice, there are several top-tier products available:

• Nucleofill – A well-known polynucleotide skin booster that enhances hydration and collagen production. Their Nucleofill Soft Plus and Nucleofill Strong are particularly sought-after.
• PhilArt – Another line of effective polynucleotide treatments that targets skin laxity and fine lines: Croma PhilArt Next and Croma PhilArt Eye are very popular.

Frequently Asked Questions

What Are Polynucleotides Used For?

Polynucleotides are used for skin rejuvenation, fine-line reduction, scar healing, and hair restoration.

What Benefits Do Polynucleotide Injections Offer?

They stimulate collagen production, improve hydration, reduce inflammation, and promote tissue repair, offering long-term benefits for skin health.

Are Polynucleotides Better Than Hyaluronic Acid Fillers?

They work differently from fillers. They focus on skin quality improvement, whereas HA fillers provide immediate volume.

How Long Do Polynucleotide Results Last?

Results typically last 6-12 months, depending on individual skin conditions and treatment protocols.

Is Polynucleotide Treatment Safe?

Yes, as a biocompatible and natural treatment, polynucleotide injections have a strong safety profile and minimal risk of adverse reactions.

Final Thoughts

Polynucleotides are reshaping the field of aesthetic medicine by offering a natural, regenerative approach to skin rejuvenation. With their ability to stimulate collagen, improve hydration, and repair tissue, they provide long-term benefits beyond what traditional fillers can achieve.

For medical aestheticians looking to enhance their treatment offerings, polynucleotide therapy is a must-have in any aesthetic practice. Explore Best Buy Fillers shop and buy polynucleotides premium products.