Polynucleotides Before and After: What to Expect from This Regenerative Treatment

Understanding Polynucleotides and Their Role in Aesthetic Medicine
Polynucleotide-based treatments have emerged as a revolutionary approach to regenerative aesthetics, offering a natural way to rejuvenate skin, improve hydration, and stimulate collagen production. Derived from purified DNA fragments, polynucleotides promote cellular repair and enhance skin elasticity, making them a sought-after solution for anti-aging and tissue regeneration.
What Body Parts Can Polynucleotides Be Used For?
Polynucleotide injection is a versatile treatment option designed to address a variety of aesthetic concerns across multiple areas of the body. These injections work by stimulating cellular repair, enhancing hydration, and promoting collagen production, making them ideal for treating delicate and aging skin. Some of the most common treatment areas include:
- Under the Eyes – One of the most popular applications, polynucleotides help reduce dark circles, fine lines, and under-eye hollowness by improving skin quality, elasticity, and hydration. This makes the eyes appear more refreshed and youthful.
- Face – Polynucleotides improve overall facial skin tone and texture, smoothing wrinkles, fine lines, and signs of fatigue while providing deep hydration that enhances radiance and firmness.
- Neck and Décolletage – These areas are particularly prone to signs of aging, such as skin laxity and a crepey texture. Polynucleotide treatments help tighten, firm, and restore a youthful appearance to the skin in these delicate regions.
- Hands – Aging hands often lose volume and develop wrinkles due to decreased collagen production. Polynucleotide injections restore lost hydration, improve skin elasticity, and reduce the appearance of veins and tendons.
- Scalp and Hair – Polynucleotides stimulate hair follicles, promote healthy hair growth, and improve overall scalp health, making them a promising treatment for individuals experiencing hair thinning or early-stage hair loss.
- Acne Scars and Stretch Marks – Due to their regenerative properties, polynucleotides can also aid in improving the appearance of scars and stretch marks by promoting tissue repair and collagen synthesis.

Key Benefits of Polynucleotide Treatments
Enhanced Skin Regeneration – Polynucleotides promote cellular repair at a deep level, accelerating the skin’s natural healing process. This makes them particularly effective for treating fine lines, wrinkles, acne scars, and areas affected by aging or sun damage. By boosting skin renewal, these treatments contribute to smoother, more youthful-looking skin over time.
- Hydration Boost – One of the most significant advantages of polynucleotide treatments is their ability to attract and retain moisture within the skin. These molecules have strong water-binding properties, ensuring long-lasting hydration that results in plumper, healthier skin. Well-hydrated skin is more resilient and less prone to developing fine lines and dullness.
- Collagen and Elastin Stimulation – Unlike traditional fillers that add immediate volume, polynucleotides work by stimulating the body’s natural collagen and elastin production. This results in gradual but long-lasting improvements in skin texture, firmness, and elasticity, making them an excellent option for individuals seeking natural-looking rejuvenation without overfilled results.
- Anti-Inflammatory and Healing Properties – Polynucleotides have been shown to possess anti-inflammatory effects, which help soothe and calm irritated or compromised skin. This makes them particularly beneficial for individuals with sensitive skin, those prone to redness, or patients recovering from laser treatments or chemical peels. Additionally, they aid in the healing of minor wounds and scarring by enhancing tissue regeneration.
- Long-Lasting and Cumulative Effects – Unlike temporary treatments that require frequent touch-ups, polynucleotide injections deliver results that continue to improve over time. As collagen and elastin levels increase, skin becomes firmer, smoother, and more resilient, with effects lasting several months or longer. A series of treatments may be recommended for optimal results, but the benefits build progressively with each session.
Polynucleotides Before and After: Expected Results
Many patients begin to notice visible improvements within the first few weeks after undergoing polynucleotide injections, with full results typically developing over several months. The treatment works at a cellular level, meaning its effects gradually enhance skin quality, hydration, and elasticity over time. Here’s a closer look at what to expect before and after polynucleotide treatments across different areas:
- Under the Eyes: Patients experience a noticeable reduction in dark circles and under-eye hollowness, along with smoother, firmer skin. The area appears brighter, more hydrated, and refreshed, reducing signs of tiredness and aging.
- Face and Neck: Polynucleotide treatments significantly improve skin tone and texture, addressing fine lines, wrinkles, and sagging. Skin becomes firmer, more supple, and retains moisture better, leading to a more youthful and revitalized appearance.
- Scalp and Hair: By stimulating hair follicles and improving scalp health, polynucleotides contribute to thicker, stronger, and healthier hair growth. This treatment is especially beneficial for individuals experiencing hair thinning or early-stage hair loss.
- Hands and Décolletage: The skin in these areas benefits from enhanced elasticity and hydration, minimizing crepey texture and making hands and the chest area appear smoother and more youthful.
- Acne Scars and Stretch Marks: Polynucleotides promote tissue repair, reducing the appearance of scars and stretch marks by encouraging new collagen formation and improving overall skin regeneration.
Unlike traditional fillers that provide instant volume, polynucleotide treatments offer progressive, long-term improvements that enhance skin quality and health. The cumulative effects of repeated treatments ensure lasting and natural rejuvenation, making them an excellent choice for patients seeking regenerative, non-volumizing aesthetic solutions.

How Do Polynucleotides Compare to Other Treatments?
Compared to hyaluronic acid fillers, which provide instant volume, polynucleotide injections focus on long-term skin health and regeneration. Similarly, platelet-rich plasma (PRP) therapy stimulates healing but lacks the hydration and direct collagen-boosting effects of polynucleotides. As a result, polynucleotide treatments are often preferred for patients looking for natural rejuvenation without excessive volume.
Safety and Considerations
Polynucleotide treatments are generally well-tolerated, with minimal downtime and low risk of adverse reactions. Mild swelling or redness at the injection site may occur but typically resolves within a few days. Since polynucleotides are biocompatible, they are suitable for most skin types, including those with sensitive skin.
Where to Buy Polynucleotides
For medical professionals looking to incorporate polynucleotide injections into their practice, high-quality products are available online. Check out our web shop and buy polynucleotides from trusted sources.
Conclusion
Polynucleotides offer a groundbreaking approach to aesthetic medicine, delivering natural, long-lasting improvements in skin quality, hydration, and elasticity. Whether used for under-eye rejuvenation, facial tightening, or hair restoration, polynucleotide injections provide before and after results that speak for themselves. With their regenerative properties and increasing popularity, they are becoming a go-to choice for medical aestheticians worldwide.
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