Can You Mix Juvederm and Revolax in the Same Patient?

Medical professionals who work with dermal fillers are frequently faced with one big dilemma. Namely, both aestheticians and their clients keep wondering whether different brands of dermal fillers can be used on a single patient. To be more precise, many professionals wonder: Can you mix Juvederm and Revolax in the same patient? Since both brands carry popular hyaluronic acid fillers used widely in clinics around the world, the question is valid. However, the answer is not that simple, and it can be both yes and no, depending on how it is done.

Although both Juvederm and Revolax are HA-based fillers, their formulations, methods of cross-linking, and post-injection behaviours vary. Aestheticians must have a good understanding of these differences if they hope to prevent issues and produce the best possible aesthetic results.

Key Differences Between Juvederm and Revolax

Although Juvederm and Revolax fillers both contain cross-linked, non-animal-based hyaluronic acid, there are many differences related to their manufacturing processes and important characteristics. Therefore, to fully understand the dilemma of Revolax filler vs Juvederm​, please take a look at the following section:

Juvederm

Juvederm fillers are produced by Allergan, one of the main players in the industry. Being part of Allergan’s powerful system, the products also use the company’s proprietary Vycross or Hylacross technology. Therefore, Juvederm fillers feature high and low molecular weight hyaluronic acid in a proprietary form, which creates an elastic gel with a smooth structure. As a result, Juvederm products are praised for their longevity, soft appearance, and easy integration into the skin. Namely, the results of some products can even last up to 24 months.

Revolax

So, what is Revolax? Revolax fillers are produced by Across Co. in South Korea. All the products are monophasic and they feature tightly cross-linked HA. The gel in Revolax fillers is both elastic and stable, providing precise placement and minimal swelling. The entire Revolax product range is  CE-certified, and besides the obvious safety, it is gaining popularity for its affordability and consistent results. Depending on the product used, the results can be visible from 6 to 18 months.

According to the differences listed above, we can conclude that Juvederm offers longer-lasting effects and a more flexible gel that aestheticians can easily work with. On the other hand, Revolax fillers deliver predictable structure and affordability. Their unique properties also mean they integrate differently into tissue, which can affect how they interact if used together.

Is Revolax Thicker than Juvederm?

A large number of aestheticians confirm that Revolax is thicker than Juvederm. In practice, this means that Revolax is perfect for increasing volume in several areas, including the cheeks, lips, and nasolabial folds. On the other hand, Juvederm is usually much easier to inject and has a smoother consistency.

Can You Mix Revolax and Juvederm?

Using Juvederm and Revolax on the same patient is generally safe, as long as aestheticians adhere to all the key clinical guidelines. In order to even get started, practitioners must understand when and how to use each of the two brands. 

To maximise safety and reach optimal results, aestheticians should follow these guidelines:

• Avoid injecting both fillers in the same anatomical plane or exact location during the same session.
• Make sure there is a proper time interval between injections if you plan to treat the same area with two different brands. Allow the first product to settle and integrate fully before you decide to inject the other one.
• Have a good understanding of each product’s characteristics in terms of viscosity, lift capacity, and integration. Juvederm and Revolax may respond differently to movement and hydration over time.

The human body can tolerate both types of fillers well, since they are both made of hyaluronic acid and can be dissolved with hyaluronidase if necessary. However, combining them carelessly can result in uneven outcomes or unwanted side effects such as migration or nodules.

When It Makes Sense to Use Both Fillers

There are several scenarios where using both Juvederm and Revolax in the same patient can be clinically justified and even advantageous:

Combining Juvederm Voluma with Revolax Deep

Juvederm Voluma brings excellent volume and lift for the cheeks, and Revolax Deep is a great solution for the treatment of lips and nasolabial folds. Using them together provides tailored results across different facial areas.

Blending Revolax Fine with Juvederm Ultra

Revolax Fine is perfect for delicate work around the lip border, whereas Juvederm Ultra may be preferred for adding volume or correcting asymmetry.

The Original Filler Is Not Available

If the time comes for touch-up appointments, and the clinic no longer carries the initial filler, a different brand can be used, provided enough time has passed and the treatment area is carefully assessed.

Patients Coming from Another Clinic

When patients come in for maintenance after receiving fillers from another clinic, it’s often necessary to work with the existing product while incorporating the practitioner’s own preferred brand.

Clinical Best Practices

Whenever aestheticians decide to use Juvederm and Revolax fillers together, they should adhere to these practices to ensure patient safety and satisfaction:

• Use separate syringes and label them clearly. Do not attempt to mix different brands into the same syringe.
• Avoid combining the products in the same treatment area unless it is absolutely necessary. If both are used in the same region, they should be placed in different planes or at separate times.
• Document everything: Record the type of filler, brand, volume, lot number, and injection site for each product.
• Avoid mixing the products in high-risk areas such as the tear trough or glabella, where vascular compromise can lead to complications.
• Educate the patient: Let the patient know which products were used and where. Transparency helps manage expectations and supports informed consent.

When to Avoid Mixing

Even though it is possible to use both fillers on the same patient, there are specific situations where doing so is simply not recommended:

Layering Different Fillers in the Same Site

Using fillers with different cross-linking technologies in the same anatomical location can lead to inconsistent results or even delayed migration.

Lack of Product Knowledge

If the practitioner is unfamiliar with one of the fillers, they may not be able to predict how it will behave after injection.

Treating Delicate or Mobile Areas

Filler placement in delicate areas requires extra precaution and careful planning. AInjecting two different fillers in high-movement regions such as the lips or the area around the eyes can result in overcorrection, uneven texture, or unnatural feel.

Dealing with High-Risk Individuals

Patients who are prone to reactions, bruising, or swelling do not respond well to product changes. Here, practitioners should stick with one brand per session to reduce the likelihood of complications.

Which is Better, Revolax or Juvederm?

As soon as you start comparing Revolax and Juvederm, you will quickly realise that there is no single solution that fits everyone. Each filler brings its own benefits, and each is suitable for a particular target market. Revolax, for example is popular because it is cost-effective and has a very smooth application, whereas Juvederm is a popular choice with patients who are more concerned with consistency and natural results. The good thing is that both fillers give long-lasting results, and the decision is made based on one’s personal wants and needs and budget.

Conclusion

With proper planning and adequate skills, medical professionals can combine Juvederm and Revolax fillers in the same patient. However, aestheticians must take into account each product’s specific properties, avoid simultaneous use in the same location, and clearly document every step of the treatment process. For clinics that use both brands, understanding when and how to apply each one can provide more flexibility and cost-effectiveness without compromising patient care. Conveniently enough, certified practitioners can order Revolax fillers from the Best Buy Fillers online store. 

References: 

Micheels P, Porcello A, Thierry Bezzola, et al. Clinical Perspectives on the Injectability of Cross-Linked Hyaluronic Acid Dermal Fillers: A Standardized Methodology for Commercial Product Benchmarking with Inter-Injector Assessments. Gels. 2024;10(2):101-101. https://www.mdpi.com/2310-2861/10/2/101

Kim JH, Kwon TR, Lee SE, et al. Comparative Evaluation of the Effectiveness of Novel Hyaluronic Acid-Polynucleotide Complex Dermal Filler. Scientific Reports. 2020;10(1):5127. https://www.nature.com/articles/s41598-020-61952-w

Uwe Wollina and Alberto Goldman. Hyaluronic Acid Dermal Fillers: Safety and Efficacy for the Treatment of Wrinkles, Aging Skin, Body Sculpturing and Medical Conditions. Clinical Medicine Reviews in Therapeutics. https://www.researchgate.net/publication/263275744_Hyaluronic_Acid_Dermal_Fillers_Safety_and_Efficacy_for_the_Treatment_of_Wrinkles_Aging_Skin_Body_Sculpturing_and_Medical_Conditions