What Is Profhilo? Skin Bio-Remodeling for Professionals

Key Takeaways

• Profhilo is a non-volumizing injectable that uses highly concentrated hyaluronic acid to deeply hydrate and rejuvenate the skin.
• It stimulates collagen and elastin production, offering long-term improvement in skin texture and firmness.
• Treatment involves two sessions, spaced four weeks apart, with minimal downtime and natural-looking results.
• Ideal for early signs of aging, Profhilo works well on the face, neck, décolletage, and hands.
• It differs from fillers and Botox by remodeling skin rather than adding volume or restricting muscle movement.

What Is Profhilo?

Profhilo is a revolutionary injectable treatment designed for skin bio-remodeling, offering a fresh approach to anti-aging. Unlike traditional dermal fillers or neurotoxins, Profhilo doesn’t volumize or paralyze facial muscles. Instead, it delivers one of the highest concentrations of pure hyaluronic acid available (64mg/2ml) to hydrate the skin from within and stimulate the natural production of collagen and elastin.

This innovative treatment spreads smoothly under the skin, enhancing overall skin quality without altering facial structure. As a result, patients experience smoother, tighter, and more radiant skin. It’s particularly popular for areas prone to laxity and creping, such as the face, neck, décolletage, and hands.

What Makes Profhilo Different?

What sets Profhilo apart from other injectables is its non-volumizing and bioremodeling effect. Traditional fillers aim to restore lost volume, while Botox temporarily freezes muscle activity. Profhilo, however, works by bio-stimulating the skin, enhancing its structure, elasticity, and hydration from within.

Another defining feature is the purity of the product. Profhilo contains no chemical cross-linking agents, making it a safer and more natural option with a lower risk of adverse reactions. This has led to fewer reports of complications, provided it’s administered correctly.

How Profhilo Treatment Works

Profhilo is typically administered using the BAP (Bio Aesthetic Points) technique, which targets five strategic injection points on each side of the face. We wrote about precise Profhilo injection points selected to maximize distribution and stimulate collagen across a wide area on our blog.

Two-Session Protocol:

• Session 1: First round of injections
• Session 2: Follow-up after four weeks to reinforce results

Most patients begin to notice improvements within a week, but the full results develop gradually over 3–6 weeks, as collagen and elastin regeneration kick in. Wondering how long does Profhilo take to work? Expect early glow effects within a few days, with structural benefits becoming more noticeable over time.

Who Is Profhilo Best For?

Profhilo is ideal for patients in their late 20s to 50s who are starting to see early signs of aging, such as dullness, dehydration, and mild skin laxity. Common concerns it addresses include:

• Crepey skin on the neck (Profhilo neck)
• Loss of firmness in the lower face
• Fine lines on the hands and décolletage
• Tired, dull complexion in the 30s (Profhilo before and after 30s)

Patients often ask, “Is Profhilo worth it?” For those seeking subtle, natural-looking improvements without the stiffness or volume that sometimes accompanies other injectables, the answer is a resounding yes.

What to Expect During and After Treatment

Profhilo injections are quick, usually completed within 15 minutes. Because of the product’s high purity and the precision of the BAP technique, the risk of bruising or swelling is minimal.

Aftercare Tips:

• Avoid strenuous exercise, saunas, or alcohol for 24 hours
• Don’t apply makeup for 12 hours
• Avoid facial massages or pressure on the treated areas for a few days

These Profhilo aftercare steps help ensure optimal results and reduce the risk of complications such as Profhilo lumps.

How Long Does Profhilo Last?

Typically, results last around 6 months, though this can vary depending on individual factors such as age, skin quality, and lifestyle habits like sun exposure or smoking. For optimal and prolonged effects, most practitioners recommend maintenance sessions every 6–9 months. These touch-up treatments help sustain hydration, firmness, and overall skin quality over time, making Profhilo a reliable option for long-term rejuvenation.

Where to Buy Profhilo

Looking to stock up for your clinic? You can buy Profhilo online from licensed aesthetic product suppliers like Best Buy Fillers.

FAQs

Is Profhilo better than Botox?

Profhilo and Botox serve different purposes. Botox relaxes muscle movement to reduce expression lines, while Profhilo rejuvenates the skin’s structure and hydration. They are often used in combination for full-face rejuvenation.

How long does Profhilo last?

Results typically last around 6 months, with maintenance treatments advised twice a year.

How much does Profhilo cost?

Prices vary depending on region and clinic, but generally range from $300 to $800 per session.

What to avoid after Profhilo?

Avoid alcohol, heavy workouts, saunas, and makeup for the first 24 hours. Follow Profhilo aftercare guidelines closely.

Where is Profhilo injected?

Common areas include the face, neck, décolletage, and hands, using precise Profhilo injection points for even distribution.

Sources

1. Maytin EV. Hyaluronan: More than just a wrinkle filler. Glycobiology. 2016;26(6):553-559. doi:10.1093/glycob/cww033 https://pubmed.ncbi.nlm.nih.gov/26964566/

2.     Stellavato A, Corsuto L, D’Agostino A, et al. Hyaluronan Hybrid Cooperative Complexes as a Novel Frontier for Cellular Bioprocesses Re-Activation. PLoS One. 2016;11(10):e0163510. Published 2016 Oct 10. doi:10.1371/journal.pone.0163510 https://pubmed.ncbi.nlm.nih.gov/27723763/

3. Cassuto D, Bellia G, Schiraldi C. An Overview of Soft Tissue Fillers for Cosmetic Dermatology: From Filling to Regenerative Medicine. Clin Cosmet Investig Dermatol. 2021;14:1857-1866. Published 2021 Dec 22. doi:10.2147/CCID.S276676 https://pubmed.ncbi.nlm.nih.gov/34992400/